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Non-invasive Blood Glucose Monitoring (Opara, Perez-Luna, Raman)
Sensor technologies that eliminate drawing blood for monitoring blood glucose concentration are very appealing to patients with diabetes and their caregivers. A sophisticated concept has been developed to draw up interstitial fluid from the body without contamination with sweat, and utilizing impedance spectroscopy to measure the glucose concentration of that fluid. First, a low-pressure vacuum would draw sweat from the skin and expel it using a piston. An ultrasound emitter would then permeate the skin and allow the vacuum to draw up interstitial fluid. The impedance of this interstitial fluid would be measured at discreet frequencies known to correspond to glucose. The device would then display the blood glucose concentration on an LCD screen and expel the assayed interstitial fluid. Lastly, self-cleaning sensors would clean the sample chamber.

 

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